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ALOE VERA INNER LEAF JUICE POWDER

TOP BENEFITS OF ALOE VERA

    • Supports skin health *
    • Supports healthy metabolism *
    • Supports gastrointestinal health *

WHAT IS ALOE VERA?

This succulent plant of the Aloe genus (also called Aloe barbadensis) is native to the southwestern United States. Around the world, it grows wild in tropical, semi-tropical, and arid climates.

 

Throughout history, aloe vera has been used in many different traditional healing systems (Ayurveda, Chinese, Egyptian, Greek, Roman, etc.), dating back several thousand years.

 

In addition to polysaccharides, vitamins, enzymes, minerals, and phenolic compounds, the fleshy leaves contain a clear gel (the juice is made from this gel) that is loaded with hundreds of bioactive compounds that are responsible for the multifunctional properties of Aloe.

 

Water and aloe polysaccharides are the main components of the gel, as well as many antioxidants, including *-tocopherol (vitamin E), ascorbic acid (vitamin C), carotenoids, flavonoids and tannins. Today's oral Aloe vera products support skin, digestive, immune, and metabolic health [1,2].

ALOE VERA KEY MECHANISMS

Skin health*

 

  • May help reduce the appearance of fine lines and wrinkles [3–6]
  • Supports skin elasticity [3,7–9]
  • Supports skin hydration [4–7]
  • Supports skin barrier function (tight junctions) [10]
  • Supports dermal extracellular matrix (ECM) structure (collagen, hyaluronic acid) [3–7,9,11–15]
  • Supports healthy transepidermal water loss (TEWL) levels [5,7]
  • Supports nail structure and health [5]
  • Supports skin in adapting to environmental stress [6,9,16]
  • Supports antioxidant defenses [17]
  • Supports Nrf-2 signaling [17]
  • Supports healthy immune/cytokine signaling [6]
  • Supports skin growth factor production (TGF-β1, EGF, bFGF, IGF-1, VEGF) [11,14,15]
  • Supports skin vascularity [11]
  • Supports injury repair functions [14]

 

Metabolic health*

 

  • Supports maintenance of healthy blood glucose levels [18–20]
  • Supports maintenance of healthy blood lipid levels [18–20]
  • Supports maintenance of healthy insulin signaling [21]
  • Supports healthy body fat levels [21]

 

Antioxidant defenses*

 

  • Supports antioxidant defenses [22–24]
  • Counters ROS production and oxidative stress [22–25]
  • Supports free radical scavenging [25,26]

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REFERENCES

[1]S.K. Kar, T.K. Bera, International Journal of Pharmaceutical Sciences and Research 9 (2018) 1416–1423.

[2]M.H. Radha, N.P. Laxmipriya, Afr. J. Tradit. Complement. Altern. Med. 5 (2015) 21–26.

[3]S. Cho, S. Lee, M.-J. Lee, D.H. Lee, C.-H. Won, S.M. Kim, J.H. Chung, Ann. Dermatol. 21 (2009) 6–11.

[4]M. Tanaka, E. Misawa, K. Yamauchi, F. Abe, C. Ishizaki, Clin. Cosmet. Investig. Dermatol. 8 (2015) 95–104.

[5]C. Kaminaka, Y. Yamamoto, M. Sakata, C. Hamamoto, E. Misawa, K. Nabeshima, M. Saito, M. Tanaka, F. Abe, M. Jinnin, J. Dermatol. 47 (2020) 998–1006.

[6]E. Misawa, M. Tanaka, M. Saito, K. Nabeshima, R. Yao, K. Yamauchi, F. Abe, Y. Yamamoto, F. Furukawa, Photodermatol. Photoimmunol. Photomed. 33 (2017) 101–111.

[7]M. Tanaka, Y. Yamamoto, E. Misawa, K. Nabeshima, M. Saito, K. Yamauchi, F. Abe, F. Furukawa, Skin Pharmacol. Physiol. 29 (2016) 309–317.

[8]M. Tanaka, Y. Yamamoto, E. Misawa, K. Nabeshima, M. Saito, K. Yamauchi, F. Abe, F. Furukawa, Clin. Cosmet. Investig. Dermatol. 9 (2016) 435–442.

[9]M. Saito, M. Tanaka, E. Misawa, R. Yao, K. Nabeshima, K. Yamauchi, F. Abe, Y. Yamamoto, F. Furukawa, Biosci. Biotechnol. Biochem. 80 (2016) 1416–1424.

[10]K. Na, E. Lkhagva-Yondon, M. Kim, Y.-R. Lim, E. Shin, C.-K. Lee, M.-S. Jeon, Scand. J. Immunol. 91 (2020) e12856.

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[12]P. Chithra, G.B. Sajithlal, G. Chandrakasan, J. Ethnopharmacol. 59 (1998) 179–186.

[13]P. Chithra, G.B. Sajithlal, G. Chandrakasan, Mol. Cell. Biochem. 181 (1998) 71–76.

[14]F. Ali, N. Wajid, M.G. Sarwar, A.M. Qazi, Curr. Pharm. Biotechnol. (2020).

[15]R. Yao, M. Tanaka, E. Misawa, M. Saito, K. Nabeshima, K. Yamauchi, F. Abe, Y. Yamamoto, F. Furukawa, J. Food Sci. 81 (2016) H2849–H2857.

[16]D. Rodrigues, A.C. Viotto, R. Checchia, A. Gomide, D. Severino, R. Itri, M.S. Baptista, W.K. Martins, Photochem. Photobiol. Sci. 15 (2016) 334–350.

[17]L. Yuan, X. Duan, R. Zhang, Y. Zhang, M. Qu, J. Dermatolog. Treat. 31 (2020) 300–308.

[18]H.F. Huseini, S. Kianbakht, R. Hajiaghaee, F.H. Dabaghian, Planta Med. 78 (2012) 311–316.

[19]S. Devaraj, M. Yimam, L.A. Brownell, I. Jialal, S. Singh, Q. Jia, Metab. Syndr. Relat. Disord. 11 (2013) 35–40.

[20]S. Alinejad-Mofrad, M. Foadoddini, S.A. Saadatjoo, M. Shayesteh, J. Diabetes Metab. Disord. 14 (2015) 22.

[21]H.-C. Choi, S.-J. Kim, K.-Y. Son, B.-J. Oh, B.-L. Cho, Nutrition 29 (2013) 1110–1114.

[22]S. Rajasekaran, K. Sivagnanam, S. Subramanian, J. Pharm. Pharmacol. 57 (2005) 241–246.

[23]N. Klaikeaw, J. Wongphoom, D. Werawatganon, M. Chayanupatkul, P. Siriviriyakul, World J. Hepatol. 12 (2020) 363–377.

[24]M. Guven, U.H. Gölge, E. Aslan, M.H. Sehitoglu, A.B. Aras, T. Akman, M. Cosar, Biomed. Pharmacother. 79 (2016) 201–207.

[25]M.-C. Kang, S.Y. Kim, Y.T. Kim, E.-A. Kim, S.-H. Lee, S.-C. Ko, W.A.J.P. Wijesinghe, K.W. Samarakoon, Y.-S. Kim, J.H. Cho, H.-S. Jang, Y.-J. Jeon, Carbohydr. Polym. 99 (2014) 365–371.

[26]A. López, M.S. de Tangil, O. Vega-Orellana, A.S. Ramírez, M. Rico, Molecules 18 (2013) 4942–4954.